A class of chemical compounds known as sulfamates is made up of the sulfamate ion (NH2SO3-). They are sulfamic acid (H3NSO3) derivatives in which organic groups or metal ions have taken the place of one or more hydrogen atoms. Sulfamates are used in a wide range of industries and sectors, such as industrial operations, agriculture, and medicines. Sulfamates are widely used in the pharmaceutical sector. Sulfamates are useful building blocks for the creation of antimicrobial medications because they have antibacterial and antifungal qualities. To treat bacterial infections, compounds like sulfamethoxazole are frequently used in conjunction with other antibiotics. Additionally, sulfamates are used in the creation of medications that aim to treat conditions including Alzheimer's and cancer. Promising possibilities for therapeutic interventions, they can inhibit certain cellular pathways and modify enzyme activity. Sulfamates are used in the manufacture of insecticides and herbicides in agriculture. Sulfometuron methyl and other similar compounds are useful in preventing weed growth in a variety of crops, which raises yields and improves agricultural productivity. Sulfamates provide a strategy to manage pests while having the least negative effects on the environment since they can specifically target particular biochemical pathways in plants.Sulfamates are also used in certain industrial operations. They help to facilitate the production of different organic molecules by acting as catalysts in chemical processes. As chelating agents, sulfamates can help with the purification and sequestration of metal ions. They are useful additions in sectors including textiles, plastics, and cosmetics because of their adaptable chemical characteristics. Several techniques are used in the synthesis of sulfamates, depending on the final product and intended use. Sulfamic acid is frequently synthesized by reacting it with metal oxides, sulfonyl chlorides, or alkyl or aryl halides. To further customize the resultant sulfamates' characteristics for particular applications, functional group transformations or derivatization might be applied.Sulfamates are widely used, yet they may be harmful to the environment and human health. It has been discovered that certain sulfamates are persistent in the environment, which may have an effect on ecosystems and human health due to bioaccumulation and biomagnification. The creation of safer substitutes and better waste management techniques are two initiatives aimed at reducing these dangers. To sum up, sulfamates are a flexible class of chemicals with a wide range of uses in industry, agriculture, and medicine. They are useful tools in chemical synthesis, crop protection, and drug development because of their distinct chemical characteristics. To guarantee their safe and sustainable usage, it is necessary to give serious thought to how they will affect the environment and human health.
