A class of organic molecules known as organomercury compounds is made up of carbon-mercury bonds. Due to their special qualities and wide range of uses as catalysts, in industrial processes, and in organic synthesis, these compounds are quite interesting. However, because of the toxicity of mercury, they also present serious risks to the environment and human health. Methylmercury, one of the most well-known organomercury compounds, is created when bacteria in aquatic settings methylate inorganic mercury. When ingested in high concentrations, methylmercury poses major health concerns to humans because it bioaccumulates in the food chain, particularly in fish. Severe neurological damage can result from it, especially in young children and pregnant fetuses. Organomercurials are a significant subclass of organomercury chemicals that are widely employed as preservatives, fungicides, and bactericides. For instance, ethylmercuric chloride and phenylmercuric acetate have been used in a variety of industrial and medicinal applications as antiseptics and disinfectants. However, because of worries about their toxicity and persistence in the environment, their use has decreased. Additionally, organomercury compounds are used as catalysts in chemical synthesis for a variety of transformations. In carbene transfer processes, for example, mercury carbenoids produced from organomercury compounds have been used to promote the synthesis of cyclopropanes and other cyclic compounds. Growing interest has been seen in creating environmentally safe and sustainable substitutes for organomercury chemicals in recent years. The goal of green chemistry techniques is to reduce or completely do away with the usage of dangerous or toxic materials, such as compounds that contain mercury, in chemical reactions. As a result, other catalysts and techniques have been developed that achieve comparable or better reaction results without using mercury.In general, worries about toxicity and environmental effects have limited the broad use of organomercury compounds, despite the fact that they have proved crucial in many other disciplines. Protecting the environment and public health requires efforts to reduce their use and create safer substitutes. Additionally, ongoing studies into the chemistry and uses of To completely comprehend their characteristics and possible advantages while minimizing their negative effects, organomercury compounds are required.