Alkyl nitrites, sometimes referred to as "poppers," are a class of substances that are mostly used for fun. These are volatile liquids with a pronounced fruity smell that are often marketed as "video head cleaners" or "room odorizers" in tiny bottles. Although they are marketed as recreational drugs, their main application is inhalation due to their vasodilator properties.An alkyl group and a nitrite group (-ONO) make up the chemical structure of alkyl nitrites. Amyl, butyl, and isobutyl nitrites are examples of common alkyl nitrites. When breathed, these chemicals cause the release of nitric oxide (NO), which relaxes smooth muscle and dilates blood vessels. This causes a rush. of blood to the brain, resulting in feelings of warmth, pleasure, and improved sex.Although alkyl nitrites are now frequently used recreationally, they were first employed in medicine as vasodilators to treat illnesses like cyanide poisoning and angina (chest pain). However, their medical use has decreased because to their potential for abuse and misuse, and they are now mostly linked to recreational drug use.Alkyl nitrites were first used as recreational drugs in the late 20th century. They were especially popular among the LGBTQ+ community, where they were used to relax the anal sphincter muscles and improve anal intercourse. Alkyl nitrites are widely used, although their safety has generated discussion and worry. Alkyl nitrite use can cause headaches, dizziness, a rapid heartbeat, and a reduction in blood pressure in the short term. Extended or overindulgent usage may result in more serious health problems, such as neurotoxicity and methemoglobinemia, a disorder in which the blood's capacity to carry oxygen is diminished.Moreover, reports of people utilizing alkyl nitrites and developing vision issues, such as transient blindness or retinal damage, have been made. It is believed that the drug's vasodilatory effects on ocular blood vessels are the cause of these visual abnormalities. Because alkyl nitrites have the potential to be abused and pose health hazards, their use and sale are regulated in many countries. They are however still offered for purchase through a number of outlets, such as internet retailers and specialized stores, where they are advertised as novelty items or leather cleansers. Alkyl nitrites are nevertheless a common recreational substance despite their hazards, especially in some subcultures.